Circular RNA hsa_circRNA_0007334 is Predicted to Promote MMP7 and COL1A1 Expression by Functioning as a miRNA Sponge in Pancreatic Ductal Adenocarcinoma
نویسندگان
چکیده
منابع مشابه
Correction: MiRNA-615-5p Functions as a Tumor Suppressor in Pancreatic Ductal Adenocarcinoma by Targeting AKT2
There is an error in Table 2. The values for " Negative, " " Weak positive, " and " Positive rate " in the " PDAC " column are incorrect. Please see the corrected Table 2 here.
متن کاملMiRNA-615-5p Functions as a Tumor Suppressor in Pancreatic Ductal Adenocarcinoma by Targeting AKT2
BACKGROUND Aberrant microRNA (miRNA) expression is associated with tumor development. This study aimed to elucidate the role of miR-615-5p in the development of pancreatic ductal adenocarcinoma (PDAC). METHODS Locked nucleic acid in situ hybridization (LNA-ISH) was performed to compare miR-615-5p expression in patients between PDAC and matched adjacent normal tissues. Effects of miR-615-5p ov...
متن کاملModulation of FoxO1 expression by miR-21 to promote growth of pancreatic ductal adenocarcinoma.
BACKGROUND Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal primary tumors in humans, with undetermined tumorigenesis. Although previous work by us, and by others, has clearly demonstrated an involvement of miR-21 in the growth of PDAC, the underlying mechanism has not been clarified. METHODS Here we analyzed the regulation of FoxO1 by miR-21 in vitro and in vivo, using lucif...
متن کاملIncreased circular RNA UBAP2 acts as a sponge of miR-143 to promote osteosarcoma progression
Deregulated expression of circular RNA (circRNA) has been determined to be important in carcinogenesis and progression; however, in the most common type of primary malignant bone tumor osteosarcoma, the roles of circRNA in cancer development still remain to be elucidated. Here, we found that circRNA UBAP2 (circUBAP2) expression is significantly increased in human osteosarcoma tissues as compare...
متن کاملIntegrated analysis of mRNA and miRNA expression profiles in pancreatic ductal adenocarcinoma.
In the present study, to investigate the potential molecular mechanism of pancreatic ductal adenocarcinoma (PDAC), mRNA and miRNA expression profiles were integrated for systematic analysis. Results showed that a total of 76 common differentially expressed genes (DEGs) were identified from 2 mRNA expression profiles that contained 39 tumor and 15 normal samples. Notably, the tumor and normal sa...
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ژورنال
عنوان ژورنال: Journal of Oncology
سال: 2019
ISSN: 1687-8450,1687-8469
DOI: 10.1155/2019/7630894